calotropis gigantea has been used as a folk medicine in India for many years, and has been reported to have a variety of uses. In Ayurveda, Indian practitioners have used the root and leaf of. procera in asthma and also used in bacterial infection, swelling with redness, boils also and shortness of breath and the bark in liver and spleen diseases. The plant is reported as effective itreating skin, digestive, respiratory, circulatory and neurological disorders and was used to treat fevers, elephantiasis, nausea, vomiting, and diarrhea. The milky juice of Calotropis procera was used against arthritis, cancer, and as an antidote for snake bite.